Senior Scientist

Job Title (Senior) Scientist

Grade Mid-Senior Grade (PhD in a Biomedical Degree)

Reports to Scientific Manager and CEO

Hours Full Time

Location The Biosphere, Newcastle Helix, Draymans Way Newcastle upon Tyne NE45BX

Website https://alcyomics.com/job-vacancies

As a Senior Scientist at a leading CRO, you will be responsible for executing high-quality, efficient, and robust client projects. You will collaborate with top-tier and emerging pharmaceutical companies to deliver advanced therapeutic testing using our proprietary Skimune® immunology-based assays. This role involves developing protocols, sourcing materials, executing experiments, and analysing data, ensuring that all client needs are met with precision.

Key responsibilities for this role include:

Client-Focused Research:

- Develop and execute in vitro experiments using the Skimune® platform, including T cell proliferation and cytokine secretion assays (e.g., MSD, Luminex, DuoSet ELISA).

- Protocol Development: Design working protocols for advanced therapeutic testing, from project scope to final report delivery.

- Data Analysis: Conduct detailed data analysis, including tissue culture, mRNA expression, and cytokine analysis, utilizing automation and software solutions (e.g., ImageJ, Python, QuPath, R, Pivot Tables, Graphpad Prism).

- Tissue Processing & Assays: Perform tissue sectioning, embedding, and Skimune® assay development, with immunohistochemistry and cytokine analysis as required.

- Collaboration & Innovation: Work with internal teams and external partners to develop innovative preclinical assays and contribute to business/commercial activities.

- Scientific Communication: Prepare research papers, reports, and presentations; deliver findings to clients, internal teams, and at scientific conferences.

- Compliance & Quality Control: Ensure compliance with ISO 9001-2015 standards, maintain accurate records, and contribute to auditing and writing Standard Operating Procedures (SOPs).

- Mentorship & Training: Set a positive example for colleagues, mentor junior staff, and ensure team success by sharing knowledge and best practices.

- Business Development Support: Assist in identifying potential R&D opportunities, contribute to grant applications, and support external collaborations.

Essential Requirements:

Technical Skills:

- Expertise in tissue culture, cytokine analysis, toxicity, immunotoxicity and immunology-based assays.

- Familiarity with data analysis principles, including data sanitation and automation.

- Experience with immunohistochemistry, tissue processing, and advanced image analysis software (ImageJ, QuPath, etc.).

- Knowledge of Python or R for data analysis is a plus.

Soft Skills:

- Strong attention to detail with the ability to manage multiple projects.

- Experience with quality control systems, including ISO9001.

- Proven ability to work independently and collaboratively within a team.

Education & Experience:

- Advanced degree (MSc/PhD) in Immunology, Molecular Biology, or related field.

- Proven experience in CRO or pharmaceutical settings, working with advanced therapeutics.

Opportunities for Growth:

- Contribute to groundbreaking research in immunology and advanced therapeutics.

- Collaborate with top pharmaceutical companies globally.

- Take on leadership and mentorship roles as the company expands.

If you are an innovative scientist with a passion for cutting-edge therapeutics and immunology, we invite you to apply and help shape the future of drug testing and therapeutic solutions.

If you want to find out more then please send your CV and covering letter to [email protected] and we can take it from there.

Job Types: Full-time, Permanent

Pay: £35,000.00-£40,000.00 per year

Benefits:

• Additional leave
• Company events
• Company pension
• On-site parking
• Sick pay

Schedule:

• Flexitime
• Monday to Friday
• Weekend availability

Ability to commute/relocate:

• Newcastle Upon Tyne: reliably commute or plan to relocate before starting work (required)

Education:

• PhD (preferred)

Experience:

• working in CRO or pharmaceutical settings: 1 year (preferred)
• tissue culture: 1 year (preferred)

Work Location: In person

Reference ID: Senior Scientist Alcyomics Ltd